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    Infection & Response

    Revision notes · Biology

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    Lesson step 1 of 4Pathogens & Disease

    Pathogens & Disease

    Pathogens are microorganisms that cause disease. There are four types:

    Bacteria — single-celled organisms that reproduce rapidly. They produce toxins that damage cells and tissues. Examples: Salmonella (food poisoning), Gonorrhoea (STI).

    Viruses — much smaller than bacteria, not living cells. They reproduce inside host cells and destroy them. Examples: Measles, HIV, Tobacco Mosaic Virus.

    Fungi — some cause disease in plants and animals. Example: Rose black spot (plants).

    Protists — single-celled eukaryotes. Example: Plasmodium (causes malaria, spread by mosquitoes).

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    Key Terms

    Pathogen
    A microorganism that causes disease (bacteria, virus, fungus, or protist).
    Antigen
    A unique protein on the surface of a pathogen that triggers an immune response.
    Antibody
    A protein produced by lymphocytes that binds to a specific antigen to destroy the pathogen.
    Vaccination
    Introducing dead/inactive pathogen to stimulate antibody production and create memory cells.
    Monoclonal antibody
    An identical antibody produced by cloning a single type of white blood cell, used in diagnosis and treatment.